Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial

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Standard

Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy : a randomised controlled phase 3 trial. / Coles, Alasdair J; Twyman, Cary L; Arnold, Douglas L; Cohen, Jeffrey A; Confavreux, Christian; Fox, Edward J; Hartung, Hans-Peter; Havrdova, Eva; Selmaj, Krzysztof W; Weiner, Howard L; Miller, Tamara; Fisher, Elizabeth; Sandbrink, Rupert; Lake, Stephen L; Margolin, David H; Oyuela, Pedro; Panzara, Michael A; Compston, D Alastair S; CARE-MS II investigators ; Sørensen, Per Soelberg.

In: Lancet, Vol. 380, No. 9856, 2012, p. 1829-39.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Coles, AJ, Twyman, CL, Arnold, DL, Cohen, JA, Confavreux, C, Fox, EJ, Hartung, H-P, Havrdova, E, Selmaj, KW, Weiner, HL, Miller, T, Fisher, E, Sandbrink, R, Lake, SL, Margolin, DH, Oyuela, P, Panzara, MA, Compston, DAS, CARE-MS II investigators & Sørensen, PS 2012, 'Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial', Lancet, vol. 380, no. 9856, pp. 1829-39. https://doi.org/10.1016/S0140-6736(12)61768-1

APA

Coles, A. J., Twyman, C. L., Arnold, D. L., Cohen, J. A., Confavreux, C., Fox, E. J., Hartung, H-P., Havrdova, E., Selmaj, K. W., Weiner, H. L., Miller, T., Fisher, E., Sandbrink, R., Lake, S. L., Margolin, D. H., Oyuela, P., Panzara, M. A., Compston, D. A. S., CARE-MS II investigators, & Sørensen, P. S. (2012). Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial. Lancet, 380(9856), 1829-39. https://doi.org/10.1016/S0140-6736(12)61768-1

Vancouver

Coles AJ, Twyman CL, Arnold DL, Cohen JA, Confavreux C, Fox EJ et al. Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial. Lancet. 2012;380(9856):1829-39. https://doi.org/10.1016/S0140-6736(12)61768-1

Author

Coles, Alasdair J ; Twyman, Cary L ; Arnold, Douglas L ; Cohen, Jeffrey A ; Confavreux, Christian ; Fox, Edward J ; Hartung, Hans-Peter ; Havrdova, Eva ; Selmaj, Krzysztof W ; Weiner, Howard L ; Miller, Tamara ; Fisher, Elizabeth ; Sandbrink, Rupert ; Lake, Stephen L ; Margolin, David H ; Oyuela, Pedro ; Panzara, Michael A ; Compston, D Alastair S ; CARE-MS II investigators ; Sørensen, Per Soelberg. / Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy : a randomised controlled phase 3 trial. In: Lancet. 2012 ; Vol. 380, No. 9856. pp. 1829-39.

Bibtex

@article{ccf251f938794250889452b7fcab2307,
title = "Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial",
abstract = "The anti-CD52 monoclonal antibody alemtuzumab reduces disease activity in previously untreated patients with relapsing-remitting multiple sclerosis. We aimed to assess efficacy and safety of alemtuzumab compared with interferon beta 1a in patients who have relapsed despite first-line treatment.",
author = "Coles, {Alasdair J} and Twyman, {Cary L} and Arnold, {Douglas L} and Cohen, {Jeffrey A} and Christian Confavreux and Fox, {Edward J} and Hans-Peter Hartung and Eva Havrdova and Selmaj, {Krzysztof W} and Weiner, {Howard L} and Tamara Miller and Elizabeth Fisher and Rupert Sandbrink and Lake, {Stephen L} and Margolin, {David H} and Pedro Oyuela and Panzara, {Michael A} and Compston, {D Alastair S} and S{\o}rensen, {Per Soelberg} and S{\o}rensen, {Per Soelberg}",
note = "Copyright {\textcopyright} 2012 Elsevier Ltd. All rights reserved.",
year = "2012",
doi = "10.1016/S0140-6736(12)61768-1",
language = "English",
volume = "380",
pages = "1829--39",
journal = "The Lancet",
issn = "0140-6736",
publisher = "TheLancet Publishing Group",
number = "9856",

}

RIS

TY - JOUR

T1 - Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy

T2 - a randomised controlled phase 3 trial

AU - Coles, Alasdair J

AU - Twyman, Cary L

AU - Arnold, Douglas L

AU - Cohen, Jeffrey A

AU - Confavreux, Christian

AU - Fox, Edward J

AU - Hartung, Hans-Peter

AU - Havrdova, Eva

AU - Selmaj, Krzysztof W

AU - Weiner, Howard L

AU - Miller, Tamara

AU - Fisher, Elizabeth

AU - Sandbrink, Rupert

AU - Lake, Stephen L

AU - Margolin, David H

AU - Oyuela, Pedro

AU - Panzara, Michael A

AU - Compston, D Alastair S

AU - CARE-MS II investigators

AU - Sørensen, Per Soelberg

N1 - Copyright © 2012 Elsevier Ltd. All rights reserved.

PY - 2012

Y1 - 2012

N2 - The anti-CD52 monoclonal antibody alemtuzumab reduces disease activity in previously untreated patients with relapsing-remitting multiple sclerosis. We aimed to assess efficacy and safety of alemtuzumab compared with interferon beta 1a in patients who have relapsed despite first-line treatment.

AB - The anti-CD52 monoclonal antibody alemtuzumab reduces disease activity in previously untreated patients with relapsing-remitting multiple sclerosis. We aimed to assess efficacy and safety of alemtuzumab compared with interferon beta 1a in patients who have relapsed despite first-line treatment.

U2 - 10.1016/S0140-6736(12)61768-1

DO - 10.1016/S0140-6736(12)61768-1

M3 - Journal article

VL - 380

SP - 1829

EP - 1839

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 9856

ER -

ID: 48584402